The VRI includes 150 researchers working on more than 40 international projects.
James Di Santo received a combined M.D./Ph.D. in 1989/1991 from Cornell University Medical College and the Memorial Sloan–Kettering Cancer Center, and completed post-doctoral training with Alain Fischer in Paris, where he characterized several genes responsible for primary human immunodeficiency syndromes.
In 1994, he joined the Institut National de la Santé et de la Recherche Médicale (Inserm) as a permanent staff scientist. In 1999, he moved his laboratory to the Immunology Department of the Institut Pasteur, where he directed the Immunology Department from 2002-2006. HIs research interests include defining the role of cytokines in lymphoid development, and understanding the differentiation of natural killer cells and other innate lymphoid cells.
In the context of the VRI, he will investigate combination immunotherapies to eliminate HIV-1 reservoirs using novel ‘humanized’ mouse models.