The VRI includes 150 researchers working on more than 40 international projects.

Preclinical models

Christiane Moog Immuno chemistrician

PhD 1990, in Immunochemistry at University Louis Pasteur, Strasbourg; post-doc at DKFZ, Heidelberg, Germany

She was hired by Synthélabo to develop the screening of anti-HIV compounds at the Institute of Virology in Strasbourg. The team was involved in numerous antiviral development to increase efficacy, limit resistance and study synergistic effects of antiviral compounds.

Christiane Moog further joined INSERM, developed her own group and created the neutralizing antibody plate-form in which experiments are performed under GcLP (good clinical laboratory practices) conditions. She notably participated in the standardization of neutralization assays and is a member of various coordinated actions: proficiency testing (coordinated by D. Montefiori), NeutNet (coordinated by G. Scarlatti) and Europrise (FP6-EC).

She is partner of several HIV vaccine projects: ANRS (Vac 02 to Vac 18), VRI LabEx (MUCOVAC), European projects (EuroVacI and EuroVacII from FP5-EC, EuroNeut41 from FP7-EC and EHVA from Horizon 2020). She was pioneer in investigating the various Fc-mediated inhibitory functions of non-neutralizing HIV-1 specific antibodies to be induced in addition or as alternative to neutralizing antibodies with the aim to develop new vaccination strategies.